Brian M. Zid

Principal Investigator / Associate Professor
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I am an Assistant Professor at UC San Diego in the department of Biochemistry.

I was born and raised outside the small town of Mountain Grove in southern Missouri. I received my BS in Chemistry from Truman State University in Kirksville, MO. From there I went to graduate school at Caltech, where I worked with Seymour Benzer to study the molecular mechinisms of caloric restriction in Drosophila. For my postdoc I joined the lab of Erin O'Shea at Harvard University so that I could explore how nutrients control gene expression at a more mechanistic level. While there, I used ribosomal profiling combined with microscopy and yeast genetics to investigate the connection between mRNA localization and translational control during glucose deprivation in yeast.


Exonuclease EXD2 in mitochondrial translation

Promoter sequences direct cytoplasmic localization and translation of mRNAs during starvation in yeast.

An integrated approach reveals regulatory controls on bacterial translation elongation

4E-BP extends lifespan upon dietary restriction by enhancing mitochondrial activity in Drosophila